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What is Polymyositis? Edit

[1][2][2]=== Polymyositis is known as the inflammatory myopathies which is known as chronic muscle inflammation accompanied by muscle weakness. This diseases affects skeletal muscles on both sides of the body.  It is rare to be seen in a person under the age of 18, in most cases the person is between the ages of 31-60. Polymyositis is also more likely to strike African American woman than any other race-gender combination

How does Polymyositis Affect the Muscular System? Edit

It affects muscles closest to the trunk or torso. This results in weakness and can be very severe. It will cause these muscle to become weak, have swelling tenderness, and have tissue damage. The exact reason why this happens is unknown, but some believe it might be related to an autoimmune infection or reaction.

Signs and Symptoms Edit

  • Difficulty swallowing.
  • Muscle pain.
  • Muscle weakness in the proximal muscles (shoulders, hips, etc.) this can make it hard to raise the arms over the head, get up from a sitting position, or climb stairs.
  • Problems with the voice (caused by weak throat muscles)
  • Shortness of breath.
  • Joint Pain.
  • Weight loss.
  • Loss of appetite.
  • Morning stiffness.

Diagnosis Edit

Blood tests is one of the main ways to diagnose someone with Polymyositis. A blood test will let your doctor know if you have elevated levels of muscle enzymes, such as creatine kinase (CK) and aldolase. Increased CK and aldolase levels can indicate muscle damage. A blood test can also detect specific autoantibodies associated with different symptoms of polymyositis, which can help in determining the best medication and treatment. They can run a blood test to know if you have elevated levels of muscle enzymes such as creatine kinase.  They can run electromyography, which is inserting a thin needle into the muscle.  They can also run a muscle biopsy, which they take a piece of your muscle tissue and it is tested in a lab.  Another way of diagnoses is to take part in a MRI which uses radio waves to get images of your muscles.

Treatment Edit

Treatment of polymyositis (PM) is empirical because of the rarity of the disease and the paucity of randomized, controlled trials. Polymyositis can be treated with high doses of corticosteroids. These corticosteroids can be given into the body through the mouth or intravenously. Intravenous Gamma Globulin has been tried but the results are mixed.


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